Use of cyclic bioisosters of purine system derivatives for treating diseases produced by disorders of niterergic and dopaminergic systems

The invention relates to application of compounds having a general structural formula: where R=  Li, Na, K, R1=-H, -NH2, -Br, -Cl, -OH, -COOH, B=-N , -CH , Z=-CH , -N , A=-N at B=-N , Z=-CH-, A=-CH at B=-N , Z=-CH-, A=-CH at B=-N , Z=-N , A=-CH at B=-CH , Z=-CH , A=-CH at B=-CH , Z=-N , and/or their...

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Hauptverfasser: ZHILOV VALERY KHAZHMURATOVICH, ZHURAVLEV SERGEI VLADIMIROVICH, POLOSIN VLADIMIR MIKHAILOVICH, MARKOV ALEXANDER NIKOLAEVICH
Format: Patent
Sprache:eng
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Zusammenfassung:The invention relates to application of compounds having a general structural formula: where R=  Li, Na, K, R1=-H, -NH2, -Br, -Cl, -OH, -COOH, B=-N , -CH , Z=-CH , -N , A=-N at B=-N , Z=-CH-, A=-CH at B=-N , Z=-CH-, A=-CH at B=-N , Z=-N , A=-CH at B=-CH , Z=-CH , A=-CH at B=-CH , Z=-N , and/or their pharmacologically acceptable salts as an active ingredient having appropriate activity with respect to nitrergic and/or dopaminergic systems, in a pharmaceutical composition as neuroprotector for improvement of the cognitive function and for normalization of psychophysiological status, as well as for treatment of a wide spectrum of psychological diseases, cardiovascular diseases, diseases caused by substance abuse, and diseases caused by a hyperactive immune system in mammals including human beings.