Compounds for the treatment of inflammatory disorders

This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.

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Bibliographische Detailangaben
Hauptverfasser: YU WENSHENG, GIRIJAVALLABHAN VINAY M, ROSNER KRISTIN E, TONG LING, LI DANSU, KOZLOWSKI JOSEPH A, YANG DE-YI, DAI CHAOYANG, SHIH NENG-YANG, ZHOU GUOWEI, CHEN LEI, FELTZ ROBERT, WONG MICHAEL K. C, KIM SEONG HEON, LAVEY BRIAN J, SIDDIQUI M. ARSHAD, POPOVICI-MULLER JANETA, SHANKAR BANDARPALLE B, RIZVI RAZIA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-α or combinations thereof.