Stabilized FGF formulations containing reducing agents

Stabilized FGF compositions are provided. The compositions comprise FGF or variant thereof and at least one reducing agent in an amount sufficient to inhibit FGF oxidation. Methods for increasing stability of FGF or variant thereof in a liquid or lyophilized composition and for increasing storage st...

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Bibliographische Detailangaben
Hauptverfasser: HAGEMAN ROBERT V, SHIRLEY BRET A, BAJWA KAMALJIT K
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Stabilized FGF compositions are provided. The compositions comprise FGF or variant thereof and at least one reducing agent in an amount sufficient to inhibit FGF oxidation. Methods for increasing stability of FGF or variant thereof in a liquid or lyophilized composition and for increasing storage stability of such a composition are also provided.