Determination of free fractions

The invention relates to methods for the determination of pharmacological properties of substances, such as, e.g., chemical substances. The invention also relates to methods and kits for use in the determination of the free fraction, fu, of pharmacologically active compounds in aqueous solutions and...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SCHUHMACHER JOACHIM, KOHLSDORFER CHRISTIAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention relates to methods for the determination of pharmacological properties of substances, such as, e.g., chemical substances. The invention also relates to methods and kits for use in the determination of the free fraction, fu, of pharmacologically active compounds in aqueous solutions and serum. The invention also relates to the above methods in which solid particles, coated with a lipophilic medium, are used.