Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of whi...
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creator | WILLIAMS GREGORY C ZHANG XIAOPING STEIN STANLEY RAMANATHAN SRINIVASAN PARANJPE PANKAJ SINKO PATRICK J MINKO TAMARA ZHANG GOUBAO PARK SEONG HEE LEIBOWITZ MICHAEL QIU BO POOYAN SHAHRAIR |
description | The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent. |
format | Patent |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents |
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