Optimised formulation of tobramycin for aerosolization

The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MALVOLTI CHIARA, GARZIA RAFFAELLA
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides a tobramycin formulation for delivery by aerosolization in the form of additive-free, isotonic solution whose pH has been optimised to ensure adequate shelf-life at room temperature. Said formulation can be advantageously used for the treatment and prophylaxis of acute and chronic endobronchial infections, in particular those caused by the bacterium Pseudomonas aeruginosa associated to lung diseases such as cystic fibrosis.