Method for identifying or designing a candidate agent that interacts with LINGO-1 polypeptide using a LINGO-1 three-dimensional structure

This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems.

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Bibliographische Detailangaben
Hauptverfasser: SOMERS WILLIAM STUART, DWYER BRIAN, PRESMAN ELEONORA, STAHL MARK, WILHELM JAMES M, MOSYAK LIDIA, ZHONG XIAOTIAN, JOHNSON MARK
Format: Patent
Sprache:eng
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Zusammenfassung:This disclosure relates to LINGO-1 polypeptides, LINGO-1 polypeptide/ligand complexes, crystals of LINGO-1 polypeptides, crystals of LINGO-1 polypeptide/ligand complexes, and related methods and software systems.