Dynamic over-voltage protection scheme for interface circuitry

In one embodiment of the invention, an integrated device has interface circuitry that includes a dynamic monitor that monitors the relative potential between (at least) two different power supplies to enable the device to react to over-voltage conditions such that appropriate selections can be made for which power supplies are selected for different components in the interface circuitry, such as output drivers and input receivers. The dynamic monitor enables over-voltage protection to be automatically implemented before the device has been configured, such as during the device's power-on state.