Astaxanthin production using fed-batch fermentation process by Phaffia rhodozyma

Disclosed is a fermentation method of astaxanthin using Phaffia rhodozyma comprising the steps of: (a) in the growing phase, feeding of a nutrient medium containing glucose or sucrose based on the specific growth rate (mu) of Phaffia rhodozyma cells, and (b) in the astaxanthin production phase, feed...

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Bibliographische Detailangaben
Hauptverfasser: HOSHINO TATSUO, SETOGUCHI YUTAKA, TAKAGI YOSHINORI
Format: Patent
Sprache:eng
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Zusammenfassung:Disclosed is a fermentation method of astaxanthin using Phaffia rhodozyma comprising the steps of: (a) in the growing phase, feeding of a nutrient medium containing glucose or sucrose based on the specific growth rate (mu) of Phaffia rhodozyma cells, and (b) in the astaxanthin production phase, feeding of the nutrient medium based on the astaxanthin production rate, while keeping the glucose concentration in the fermentation broth almost 0 g/L during the whole fermentation period.