Combination kit used in the treatment of malaria

A combination kit for the treatment of malaria caused by Plasmodium vivax (P. vivax) having individual doses of an anti-malarial agent, 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I) in the form of capsules; individual doses of the anti-malarial agent, ch...

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Hauptverfasser: DWIVEDI ANIL KUMAR, PANDEY VIKASH CHANDRA, PIRAMAL SWATI AJAY, SRIVASTAVA PRATIMA, ASTHANA OMKAR PRASAD, PURI SUNIL KUMAR, SRIVASTAVA SUDHIR, BHADURI AMIYA PRASAD, GUPTA RAM CHANDRA, PINTO FRANCIS JOSEPH, DUTTA GURU PRASAD, SRIVASTAVA JAGDISHWAR SAHAI, PRATAP RAM, SINGH SATYAWAN, SINGH SHIO KUMAR, THAPLIYAL HARSH PATI
Format: Patent
Sprache:eng
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Zusammenfassung:A combination kit for the treatment of malaria caused by Plasmodium vivax (P. vivax) having individual doses of an anti-malarial agent, 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I) in the form of capsules; individual doses of the anti-malarial agent, chloroquine in the form of tablets; and instruction material for the administration of the two anti-malarial drugs. The combination kit is particularly suited for a 6 days treatment regimen where the treatment is rendered by five tablets containing 500 mg of chloroquine phosphate (equivalent to 300 mg base), three to be taken on day one and one each on days two and three; and five capsules containing 25 mg of 3-[1-[[4-[(6-methoxy-8-quinolinyl)amino]pentyl]amino]ethylidene]-dihydro-2(3H)-furanone (I), one each to be taken on days two to six.