Process for the synthesis of Losartan potassium

Improved processes using primary, secondary and tertiary alcohols and with safer mode of introduction of the reagent and reaction conditions are described. Further, the process of manufacture of Losartan potassium by use of alkali metal salt such as Potassium carbonate is disclosed. A process for pr...

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Hauptverfasser: PANDA NALINAKSHYA BALARAM, UPARE ABHAY ATMARAM, SINGH RAJESH KUMAR KESHAVA PRASAD, SAXENA ASHVINI KUMAR NAND KISHORE, NIMBALKAR MANMOHAN MADHAVRAO, SOUDAGAR SATISH RAJANIKANT, KUMAR ASHOK
Format: Patent
Sprache:eng
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Zusammenfassung:Improved processes using primary, secondary and tertiary alcohols and with safer mode of introduction of the reagent and reaction conditions are described. Further, the process of manufacture of Losartan potassium by use of alkali metal salt such as Potassium carbonate is disclosed. A process for preparation of the polymorphic Form I of Losartan potassium is also disclosed herein.