Anti-dermatophytic preparation and use thereof

The present invention provides an improved preparation based on the synergistic action of garlic extract and essential oil of M. spicata var. Ganga or cinnamon oil against dermatophytic fungus. More particularly, the present invention relates to the synergistic enhancement of activity of a combinati...

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Hauptverfasser: PAL ANIRBAN, AGARWAL VINAY KUMAR, KHANUJA SUMAN PREET SINGH, GUPTA SUBHASH CHANDRA, TRIPATHY ARUN KUMAR, SHASANY AJIT KUMAR, BANSAL RAVI PRAKASH, DAROKAR MAHENDRA PANDURANG, GUPTA VIVEK KUMAR, SINGH ANIL KUMAR, SAIKIA DHARMENDRA, CHATURVEDI PUSHPLATA, AGGARWAL KRISHNA KUMAR
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention provides an improved preparation based on the synergistic action of garlic extract and essential oil of M. spicata var. Ganga or cinnamon oil against dermatophytic fungus. More particularly, the present invention relates to the synergistic enhancement of activity of a combination by menthyl acetate or Geraniol. The invention also provides a method of preparation of the synergistic combination and the shelf life observed to be more than one year. The cream based preparation is a potent anti-dermatophytic as described and illustrated by in vitro and in vivo evaluations.