Fluorescence polarization assay

The present invention relates to methods for detecting the presence of one or more analytes of interest in a sample by measuring changes in fluorescence anisotropy as a result of binding of the analytes to specific aptamers. The aptamers are immobilized on a solid support and may be in the form of a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SEKAR MICHAEL M. A, GREENFIELD I. LAWRENCE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to methods for detecting the presence of one or more analytes of interest in a sample by measuring changes in fluorescence anisotropy as a result of binding of the analytes to specific aptamers. The aptamers are immobilized on a solid support and may be in the form of an array.