Methods for the synthesis of pyridoxamine

The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods fo...

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Bibliographische Detailangaben
Hauptverfasser: KHALIFAH RAJA, KOELLNER CHRISTOPH, KEILITZ ROLAND, DEGENHARDT THORSTEN, BRAND STEPHEN ROBERT
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The invention provides non-oxidative methods for the large scale manufacture of pyridoxamine (I) (4-aminomethyl-3-hydroxy-5-hydroxymethyl-2-methylpyridine): and salts thereof. The invention also provides intermediate compounds for the synthesis of pyridoxamine, as well as compositions and methods for the treatment and/or prevention of conditions associated with the formation of post-Amadori advanced glycation end-products.