Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts

Process for the preparation of [R-(E)-1-[[[1-[3-[2-[7-chloro-2-quinolinyl]ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid (Montelukast) and its pharmaceutically acceptable salts

The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X-CN or CONH2.

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Bibliographische Detailangaben
Hauptverfasser: AAVULA SANJEEV KUMAR, KASTURI RAVI KUMAR, RAJAN SRINIVASAN THIRUMALAI, SUNDARAM VENKATARAMAN, SRIVASTAV ALOKKUMAR, BULUSU VEERA VENKATA NAGA CHANDRA SEKHAR
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:The present invention is related to a process for preparing montelukast involving the compound of formula (VI): wherein X-CN or CONH2.