Polymorph of (1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-y1] methyl piperidine hydrochloride (Donepezil hydrochloride) and a process for producing thereof

The present invention discloses a novel, stable polymorph of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride commonly known as Donepezil hydrochloride. Further the present invention discloses a process for producing Donepezil HCl amorphous and its polymorph Form (VI).

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Bibliographische Detailangaben
Hauptverfasser: SAWANT KAMLESH DIGAMBAR, AHER UMESH P, TARUR VENKATASUBRAMANIAN R, SATHE DHANANJAY GOVIND, NAIDU AVINASH VENKATARAMAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention discloses a novel, stable polymorph of 1-benzyl-4-[(5,6-dimethoxy-1-indanone)-2-yl] methyl piperidine hydrochloride commonly known as Donepezil hydrochloride. Further the present invention discloses a process for producing Donepezil HCl amorphous and its polymorph Form (VI).