Nucleic acid molecule

The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. h...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: CANCILLA MICHAEL ROBERT, CHOO KONG-HONG ANDY, DU SART DESIREE
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed generally to an isolated nucleic acid molecule encompassing a neocentromere or a functional derivative thereof or a latent, synthetic or hybrid form thereof and its use inter alia in developing a range of eukaryotic artificial chromosomes including mammalian (e.g. human) and non-mammalian an artificial chromosomes. Such artificial chromosomes are useful in a range of genetic therapies.