Production of soluble keratin derivaties

A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, an...

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Hauptverfasser: SINGLETON DIANE JOYCE, RANKIN DOUGLAS ALEXANDER, MESMAN PAUL JOHANNES ROY, SUMMERS CONAL GARTH, RODDICK-LANZILOTTA ALISA DAWN, KELLY ROBERT JAMES, ELLIS GREGORY DAVID, WORTH GILLIAN HELEN
Format: Patent
Sprache:eng
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Zusammenfassung:A process for the preparation of soluble proteins of high molecular weight with little or no damage to the structural integrity of the proteins. The process is economically and environmentally acceptable by virtue of the cost of reagents that are used, and the recycling of some of those reagents, and is suitable for the production of soluble proteins on a large scale. The process includes a first stage using oxidative sulfitolysis followed by a second stage using mild conditions to extract the soluble protein. In the case of wool as the protein source the process leads to the production of soluble keratin proteins fractionated into the classes S-sulfonated keratin intermediate filament proteins and S-sulfonated keratin high sulfur proteins.