Process for the preparation of echinocandin derivatives

A subject of the invention is a process for the preparation of the compounds of formula (I): R being as defined in the description as well as their salts, the intermediates, the use of the dihydrochloride as a medicament and the pharmaceutical compositions containing them. The process for preparing...

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Hauptverfasser: BOFFELLI PHILIPPE, BROUILLARD AGNES, DROUX SERGE, FERROUD DIDIER, PALADINO JOSEPH, COLLADANT COLETTE, LEMAITRE GUY, ELTER MICHEL
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creator BOFFELLI PHILIPPE
BROUILLARD AGNES
DROUX SERGE
FERROUD DIDIER
PALADINO JOSEPH
COLLADANT COLETTE
LEMAITRE GUY
ELTER MICHEL
description A subject of the invention is a process for the preparation of the compounds of formula (I): R being as defined in the description as well as their salts, the intermediates, the use of the dihydrochloride as a medicament and the pharmaceutical compositions containing them. The process for preparing formula (I) leads to greater than 50% yields of isomer A, and its intended use, e.g. as an antifungal medicament.
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subjects CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Process for the preparation of echinocandin derivatives
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