Sulfonamide substituted xanthine derivatives

The present invention is a sulfonamide substituted xanthine derivative of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is lower alkyl, lower alkyl substituted by phenyl, or lower alkyl substituted by halogen substituted phenyl; R2 is lower alkyl or lower alkyl substituted by...

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Bibliographische Detailangaben
Hauptverfasser: YUN WEIYA, FOLEY LOUISE H, HUBY NICHOLAS J. S, PIETRANICO-COLE SHERRIE L, DUNTEN PETER W
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention is a sulfonamide substituted xanthine derivative of formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is lower alkyl, lower alkyl substituted by phenyl, or lower alkyl substituted by halogen substituted phenyl; R2 is lower alkyl or lower alkyl substituted by lower cycloalkyl; and R3 is: Compounds of formula I and pharmaceutically acceptable salts or prodrugs thereof show activity as modulators of gluconeogenesis.