6,7-Oxygenated steroids and uses related thereto

6,7-Oxygenated steroids and uses related thereto

Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stere...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BURGOYNE DAVID L, SHEN YAPING, ROGERS CHRISTINE, PIERS EDWARD, LANGLANDS JOHN M, CHAU JOSEPH H L, SALARI HASSAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
STEROIDS
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Beschreibung
Zusammenfassung:Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 and C7, and some have specific stereochemistries such as 6alpha and 7beta oxygen substitution, and an alpha hydrogen at the 5 position in addition to having 6alpha and 7beta oxygen substitution. Steroids having 3,4-epoxy functionality are also disclosed. In addition, steroids having C17 pyran and delta-lactone functionality, with oxygen substitution at C6 and C7, or at C15, of the steroid nucleus, are disclosed.