CXCR3 antagonists

Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: LIU JIWEN, ZHU LIUSHENG, LI AN-RONG, HUANG ALAN XI, MEDINA JULIO C, MARCUS ANDREW P, JOHNSON MICHAEL G
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:Compounds, compositions and methods that are useful in the treatment of inflammatory and immune conditions and diseases are provided herein. In particular, the invention provides compounds which modulate the expression and/or function of a chemokine receptor. The subject methods are useful for the treatment of inflammatory and immunoregulatory disorders and diseases, such as multiple sclerosis, rheumatoid arthritis and type I diabetes.