Flint polypeptide analogs

Flint polypeptide analogs

Disclosed are polypeptide analogs of FLINT, polydeoxynucleotides encoding FLINT analogs, and methods of using FLINT analogs and polydeoxynucleotides. The FLINT analogs of the invention include polypeptides having the amino acid sequence of FLINT, modified at one or more positions with amino acid sub...

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Bibliographische Detailangaben
Hauptverfasser: WROBLEWSKI VICTOR JOHN, NOBLITT TIMOTHY WAYNE, COHEN FREDRIC JAY, GONZALEZ-DEWHITT PATRICIA ANN, HALE JOHN EDWARD, NEWTON CHRISTY MICHELLE, BECKER GERALD WAYNE, RATHNACHALAM RADHAKRISHNAN, MICANOVIC RADMILA, TSCHANG SHENG-HUNG RAINBOW, WITCHER DERRICK RYAN
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
PEPTIDES
SUGARS
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Beschreibung
Zusammenfassung:Disclosed are polypeptide analogs of FLINT, polydeoxynucleotides encoding FLINT analogs, and methods of using FLINT analogs and polydeoxynucleotides. The FLINT analogs of the invention include polypeptides having the amino acid sequence of FLINT, modified at one or more positions with amino acid substitutions, and include fragments thereof, as well as Fc fusions comprising FLINT and FLINT analogs.