Amidino compounds useful as nitric oxide synthase inhibitors

The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of m...

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Hauptverfasser: DURLEY RICHARD C, BERGMANIS ARIJA A, HANSEN, JR. DONALD W, SNYDER JEFFREY S, WEBBER RONALD KEITH, SCHARTMAN RICHARD R, AWASTHI ALOK K, MOORMANN ALAN E, TRIVEDI MAHIMA, FOK KAM F, TSYMBALOV SOFYA, TJOENG FOE SIONG, HICKORY BRIAN S, GANSER SCOTT S, MANNING PAMELA T, PITZELE BARNETT S, HAGEN TIMOTHY J, PROMO MICHELLE A, MAO MICHAEL, HALLINAN E. ANN, SCHOLTEN JEFFREY A, TOTH MIHALY V
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creator DURLEY RICHARD C
BERGMANIS ARIJA A
HANSEN, JR. DONALD W
SNYDER JEFFREY S
WEBBER RONALD KEITH
SCHARTMAN RICHARD R
AWASTHI ALOK K
MOORMANN ALAN E
TRIVEDI MAHIMA
FOK KAM F
TSYMBALOV SOFYA
TJOENG FOE SIONG
HICKORY BRIAN S
GANSER SCOTT S
MANNING PAMELA T
PITZELE BARNETT S
HAGEN TIMOTHY J
PROMO MICHELLE A
MAO MICHAEL
HALLINAN E. ANN
SCHOLTEN JEFFREY A
TOTH MIHALY V
description The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Amidino compounds useful as nitric oxide synthase inhibitors
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