Amidino compounds useful as nitric oxide synthase inhibitors

The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of m...

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Hauptverfasser: DURLEY RICHARD C, BERGMANIS ARIJA A, HANSEN, JR. DONALD W, SNYDER JEFFREY S, WEBBER RONALD KEITH, SCHARTMAN RICHARD R, AWASTHI ALOK K, MOORMANN ALAN E, TRIVEDI MAHIMA, FOK KAM F, TSYMBALOV SOFYA, TJOENG FOE SIONG, HICKORY BRIAN S, GANSER SCOTT S, MANNING PAMELA T, PITZELE BARNETT S, HAGEN TIMOTHY J, PROMO MICHELLE A, MAO MICHAEL, HALLINAN E. ANN, SCHOLTEN JEFFREY A, TOTH MIHALY V
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to amidino compounds and salts and prodrugs thereof. In another embodiment the present invention also provides a use of the present compounds in therapy, particular as nitric oxide synthase inhibitors. In a further embodiment, the present invention provides methods of making the amidino compounds.