N-heterocyclic derivatives as NOS inhibitors

N-heterocyclic derivatives as NOS inhibitors

N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing...

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Hauptverfasser: MCMILLAN KIRK, YE BIN, ZHAO ZUCHUN, DOLLE, III ROLAND ELLWOOD, ERICKSON SHAWN DAVID, DAVEY DAVID D, DEVLIN JAMES J, OHLMEYER MICHAEL H. J, PAN GONGHUA, MORRISSEY MICHAEL M, PARADKAR VIDYADHAR MADHAV, PARKINSON JOHN, PHILLIPS GARY B, ARNAIZ DAMIAN O, BALDWIN JOHN J
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:N-Heterocyclic derivatives of the formula (I): are described herein, as well as other N-heterocycles, as inhibitors of nitric oxide synthase. Pharmaceutical compositions containing these compounds, methods of using these compounds as inhibitors of nitric oxide synthase and processes for synthesizing these compounds are also described herein.