Substituted tricyclics

A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.

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Hauptverfasser: BEIGHT DOUGLAS WADE, ANDERSON BENJAMIN ALAN, DENNEY MICHAEL LYLE, RICHETT MICHAEL ENRICO, PHILLIPS MICHAEL LEROY, BASTIAN JOLIE ANNE, SALL DANIEL JON, DRAHEIM SUSAN ELIZABETH, MCGILL, III JOHN MCNEILL, MIHELICH EDWARD DAVID, VASILEFF ROBERT THEODORE, BACH NICHOLAS JAMES, SAWYER JASON SCOTT, KINNICK MICHAEL DEAN, MORIN, JR. JOHN MICHAEL, DILLARD ROBERT DELANE, HITE GARY ALAN, HARN NANCY KAY, SCHEVITZ RICHARD WALTER, SUAREZ TULIO, HARPER RICHARD WALTZ, LONCHARICH RICHARD JAMES, LIN HO-SHEN
Format: Patent
Sprache:eng
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Zusammenfassung:A class of novel tricyclics is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of conditions such as septic shock.