Process for preparing enantiomerically pure (S)-3-hydroxy-gamma-butyrolactone
The present invention relates to a process for the in situ preparation of optically pure (S)-3,4-dihydroxybutyric acid derivatives represented by the Formula [2] and more particularly, to a process which enables preparing optically pure (S)-3-hydroxy-gamma-butyrolactone represented by Formula [1] by...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | The present invention relates to a process for the in situ preparation of optically pure (S)-3,4-dihydroxybutyric acid derivatives represented by the Formula [2] and more particularly, to a process which enables preparing optically pure (S)-3-hydroxy-gamma-butyrolactone represented by Formula [1] by oxidation of alpha- or beta-(1,4) linked disaccharide or oligosaccharide with an oxidant under basic condition to give acid and cyclization sequentially under acidic condition to give (S)-3-hydroxy-gamma-butyrolactone. |
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