Plasminogen activator inhibitor antagonists

Compounds and pharmaceutical compositions useful as plasminogen activator inhibitor (PAI) antagonists are provided. In particular, methods of antagonizing PAI with substituted and unsubstituted aryl and heteroaryl ethers and thioethers, benzils, benzyl ethers, benzoate esters, sulfones and benzophen...

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Hauptverfasser: MADISON EDWIN L, PRYOR KENT E, BRUNCK TERENCE K, DUNCAN DAVID F, LEWIS, II RONALD D, LAWRENCE C. MAXWELL, LIM-WILBY MARGUERITA, SEMPLE JOSEPH EDWARD
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Sprache:eng
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Zusammenfassung:Compounds and pharmaceutical compositions useful as plasminogen activator inhibitor (PAI) antagonists are provided. In particular, methods of antagonizing PAI with substituted and unsubstituted aryl and heteroaryl ethers and thioethers, benzils, benzyl ethers, benzoate esters, sulfones and benzophenones are provided.