Active substance patch, kind to the skin, for transdermal administration of nonsteroidal antirheumatics

An active substance matrix patch for controlled delivery of nonsteroidal antirheumatics to the skin, comprising a flexible cover layer and a water insoluble, pressure sensitively adhesive active substance matrix, wherein said adhesive matrix is free from mineral oils and tackifier resins and is composed ofa) from 25 to 90% by weight of synthetic framework polymers based on polyisobutylene,b) from 5 to 40% by weight of amorphous poly-alpha-olefin,c) from 10 to 60% by weight of an insoluble hydrophilic filler having an average particle size of less than 100 mum, andd) from 0.001 to 20% by weight of a drug.