N-[2-hydroxy-3-(1-piperidinyl)propoxy]pyridine-1-oxide-3-carboximidoyl chloride and its use in the treatment of insulin resistance

N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers, and the addition salts thereof, pharmaceutical compositions containing the same, methods of treating pathological insulin resistance, methods of treating pathological insulin resistance and patholog...

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Hauptverfasser: NAGY KAROLY, KUERTHY MARIA, TOEROEK MAGDOLNA, NAGY MELINDA, NAGY ZOLTAN, UEROEGDI LASZLO, KOMAROMI ANDRAS, CSAKAI ZITA, MARVANYOS EDE, BARABAS MIHALY, MOGYOROSI TAMAS, KARDOS MIHALYNE, KORANYI LASZLO, SZILBEREKY JENOE, BIRO KATALIN
Format: Patent
Sprache:eng
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Zusammenfassung:N-[2-hydroxy-3-(1-piperidinyl)-propoxy]-pyridine-1-oxide-3-carboximidoyl chloride, its stereoisomers, and the addition salts thereof, pharmaceutical compositions containing the same, methods of treating pathological insulin resistance, methods of treating pathological insulin resistance and pathological conditions associated therewith, and methods of treating pathological insulin resistance by simultaneously treating diabetes-induced chronic complications, especially retinopathy, neuropathy and nephropathy, and/or by simultaneously increasing pathologically decreased peripheral neuroregeneration caused by diabetes.