Derivatives of quinoline as alpha-2 antagonists

Derivatives of quinoline as alpha-2 antagonists

A compound of formula I,wherein A, Ra, Rb, R1 to R5, m and t are as defined as disclosed, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds I can be used for the treatment of diseases or conditions where alpha-2 antagonists are indicated to be eff...

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Bibliographische Detailangaben
Hauptverfasser: WURSTER SIEGFRIED, HOEGLUND IISA, SAVOLA JUHA-MATTI, HAAPALINNA ANTTI, SALLINEN JUKKA, HOFFREN ANNA-MARJA KATARIINA, ENGSTROEM MIA, SALO HARRI ELIAS, TAUBER ANDREI YURIEVITCH
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A compound of formula I,wherein A, Ra, Rb, R1 to R5, m and t are as defined as disclosed, or a pharmaceutically acceptable salt or ester thereof, useful as an alpha-2 antagonist. The compounds I can be used for the treatment of diseases or conditions where alpha-2 antagonists are indicated to be effective.