Neuraminidase inhibitors

Neuraminidase inhibitors

The present invention provides compounds of formula Ia and Ibor a pharmaceutically acceptable salt, prodrug, or ester thereof, useful in the inhibition of neuraminidase enzymes from disease-causing microorganisms, especially influenza neuraminidase, pharmaceutical formulations containing same, proce...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: MADIGAN DAROLD L, SUN MINGHUA, WANG JIANCHIO, GIRANDA VINCENT L, WANG GARY T, STOLL VINCENT S, GU YU GUI, MARING CLARENCE J, STEWART KENT, KEMPF DALE J, HANESSIAN STEPHEN, ZHAO CHEN
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention provides compounds of formula Ia and Ibor a pharmaceutically acceptable salt, prodrug, or ester thereof, useful in the inhibition of neuraminidase enzymes from disease-causing microorganisms, especially influenza neuraminidase, pharmaceutical formulations containing same, processes and intermediates for preparing said compounds, as well as methods of using said compounds, including preventing and treating diseases caused by microorganisms having said neuraminidase enzyme.