High-resolution retina imaging and eye aberration diagnostics using stochastic parallel perturbation gradient descent optimization adaptive optics

An ocular refractive alteration device is controlled to alter an ocular refractive lens according to an eye of a patient, including applying to the eye a measuring light beam formed of incoherent light to provide an applied incoherent measuring light beam and determining an image quality metric according to the applied incoherent light beam. The ocular refractive lens alteration device is controlled to alter the refractive lens according to the image quality metric. A method is set forth for locating a tumor in-an eye including applying to the eye a measuring light beam formed of incoherent light to provide an applied incoherent measuring light beam and determining a frequency distribution is also set forth the applied incoherent measuring light beam. The tumor is locating according to the frequency distribution.