Piperazine derivatives as modulators of chemokine receptor activity

The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related d...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BROUGH STEPHEN J, MCINALLY THOMAS, BAXTER ANDREW J G, KINDON NICHOLAS D, ROBERTS BRYAN
Format: Patent
Sprache:eng
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator BROUGH STEPHEN J
MCINALLY THOMAS
BAXTER ANDREW J G
KINDON NICHOLAS D
ROBERTS BRYAN
description The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_US6562825B1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>US6562825B1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_US6562825B13</originalsourceid><addsrcrecordid>eNrjZHAOyCxILUqsysxLVUhJLcosSyzJLEstVkgsVsjNTynNSSzJLypWyE9TSM5Izc3PBikrSk1OLQAKKyQmA9VmllTyMLCmJeYUp_JCaW4GBTfXEGcP3dSC_PjU4oLE5NS81JL40GAzUzMjCyNTJ0NjIpQAAIAyMxI</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>Piperazine derivatives as modulators of chemokine receptor activity</title><source>esp@cenet</source><creator>BROUGH STEPHEN J ; MCINALLY THOMAS ; BAXTER ANDREW J G ; KINDON NICHOLAS D ; ROBERTS BRYAN</creator><creatorcontrib>BROUGH STEPHEN J ; MCINALLY THOMAS ; BAXTER ANDREW J G ; KINDON NICHOLAS D ; ROBERTS BRYAN</creatorcontrib><description>The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.</description><edition>7</edition><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2003</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20030513&amp;DB=EPODOC&amp;CC=US&amp;NR=6562825B1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76289</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20030513&amp;DB=EPODOC&amp;CC=US&amp;NR=6562825B1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>BROUGH STEPHEN J</creatorcontrib><creatorcontrib>MCINALLY THOMAS</creatorcontrib><creatorcontrib>BAXTER ANDREW J G</creatorcontrib><creatorcontrib>KINDON NICHOLAS D</creatorcontrib><creatorcontrib>ROBERTS BRYAN</creatorcontrib><title>Piperazine derivatives as modulators of chemokine receptor activity</title><description>The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2003</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZHAOyCxILUqsysxLVUhJLcosSyzJLEstVkgsVsjNTynNSSzJLypWyE9TSM5Izc3PBikrSk1OLQAKKyQmA9VmllTyMLCmJeYUp_JCaW4GBTfXEGcP3dSC_PjU4oLE5NS81JL40GAzUzMjCyNTJ0NjIpQAAIAyMxI</recordid><startdate>20030513</startdate><enddate>20030513</enddate><creator>BROUGH STEPHEN J</creator><creator>MCINALLY THOMAS</creator><creator>BAXTER ANDREW J G</creator><creator>KINDON NICHOLAS D</creator><creator>ROBERTS BRYAN</creator><scope>EVB</scope></search><sort><creationdate>20030513</creationdate><title>Piperazine derivatives as modulators of chemokine receptor activity</title><author>BROUGH STEPHEN J ; MCINALLY THOMAS ; BAXTER ANDREW J G ; KINDON NICHOLAS D ; ROBERTS BRYAN</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_US6562825B13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2003</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>BROUGH STEPHEN J</creatorcontrib><creatorcontrib>MCINALLY THOMAS</creatorcontrib><creatorcontrib>BAXTER ANDREW J G</creatorcontrib><creatorcontrib>KINDON NICHOLAS D</creatorcontrib><creatorcontrib>ROBERTS BRYAN</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>BROUGH STEPHEN J</au><au>MCINALLY THOMAS</au><au>BAXTER ANDREW J G</au><au>KINDON NICHOLAS D</au><au>ROBERTS BRYAN</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Piperazine derivatives as modulators of chemokine receptor activity</title><date>2003-05-13</date><risdate>2003</risdate><abstract>The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.</abstract><edition>7</edition><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng
recordid cdi_epo_espacenet_US6562825B1
source esp@cenet
subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Piperazine derivatives as modulators of chemokine receptor activity
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-12T14%3A46%3A10IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=BROUGH%20STEPHEN%20J&rft.date=2003-05-13&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3EUS6562825B1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true