Piperazine derivatives as modulators of chemokine receptor activity

The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related d...

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Bibliographische Detailangaben
Hauptverfasser:	BROUGH STEPHEN J, MCINALLY THOMAS, BAXTER ANDREW J G, KINDON NICHOLAS D, ROBERTS BRYAN
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention provides compounds of general formula (I)wherein R1, R2, R3, R4, R5, X, Y, Z, m and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy, especially for the treatment of chemokine receptor related diseases and conditions.