Single isomer methylphenidate and resolution process

Single isomer methylphenidate and resolution process

Single isomer methylphenidate, selected from the d- and l-threo-enantiomers, has been obtained in purified form, to the extent of less than 2% by weight of a contaminant selected from resolving agent and ritalinic acid. This is achieved by resolution of a mixture of enantiomers using an O, O'-d...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ZAVAREH HOOSHANG, HARRIS MICHAEL CHRISTOPHER JAMES
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:Single isomer methylphenidate, selected from the d- and l-threo-enantiomers, has been obtained in purified form, to the extent of less than 2% by weight of a contaminant selected from resolving agent and ritalinic acid. This is achieved by resolution of a mixture of enantiomers using an O, O'-diaroyltartaric acid as resolving agent.