Process for formulation of antibiotic compounds

The present invention involves a process for preparing a stable final formulation product of a compound of formula I,or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.

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Bibliographische Detailangaben
Hauptverfasser:	PATEL HIREN S, KANIKE ANAND, ILLIG KATHLEEN J, AL-DEHNEH ANTHONY S, HUNKE WILLIAM A, REYNOLDS SCOTT D, TSINONTIDES STELIOS C
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention involves a process for preparing a stable final formulation product of a compound of formula I,or its pharmaceutically acceptable salt, hydrate or solvate by incorporating a suitable carbon dioxide source to an unstable monosodium adduct of carbapenem antibiotic compound.