Azithromycin preparation in its noncryst alline and crystalline dihydrate forms

Azithromycin preparation in its noncryst alline and crystalline dihydrate forms

The present invention describes new procedures for the preparation of the macrolide azithromycin in its non-crystalline and crystalline dihydrate forms, which are characterized and clearly differentiated by means of the following methods and techniques:1. IR Spectroscopy.2. Differential Scan Calorim...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BAYOD JASANADA MIGUEL SANTOS, MARI FELIX FERNANDEX, GARCIA ISIDRO LLORENTE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The present invention describes new procedures for the preparation of the macrolide azithromycin in its non-crystalline and crystalline dihydrate forms, which are characterized and clearly differentiated by means of the following methods and techniques:1. IR Spectroscopy.2. Differential Scan Calorimetry (DSC).3. X-Ray Diffraction.4. Hygroscopicity.5. Crystallinity test (Light Polarized Microscopy)