Styryl benzimidazole derivatives

Styryl benzimidazole derivatives

Disclosed herein are compounds of the formula:whereinR is phenyl or substituted phenyl;or R is furyl, pyridyl or quinolinyl;R1 and R2 are hydrogen, halogen, alkyl, alkoxy, nitro, carboxyl, alkoxy-carbonyl or aryloxycarbonyl;R3 is hydrogen, alkyl, aryl or arylalkyl;R4 and R5 are hydrogen or alkyl;or...

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Hauptverfasser: ELOKDAH HASSAN M, SULKOWSKI THEODORE S, CHAI SIE-YEARL
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Disclosed herein are compounds of the formula:whereinR is phenyl or substituted phenyl;or R is furyl, pyridyl or quinolinyl;R1 and R2 are hydrogen, halogen, alkyl, alkoxy, nitro, carboxyl, alkoxy-carbonyl or aryloxycarbonyl;R3 is hydrogen, alkyl, aryl or arylalkyl;R4 and R5 are hydrogen or alkyl;or a pharmaceutically acceptable salt thereof, which are useful as inhibitors of smooth muscle cell proliferation.