Synthesis of carbamate ketolide antibiotics

Synthesis of carbamate ketolide antibiotics

The invention relates to a method of preparing a macrolide antibiotic of the formulawherein R1, R2, R3, R4, R5 are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compound...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RIPIN DAVID H. B, MCMILLEN WILLIAM T, VANDERPLAS BRIAN C, MCLAUGHLIN ROBERT W, KANEKO TAKUSHI
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
DERIVATIVES THEREOF
METALLURGY
NUCLEIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC CHEMISTRY
SUGARS
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Beschreibung
Zusammenfassung:The invention relates to a method of preparing a macrolide antibiotic of the formulawherein R1, R2, R3, R4, R5 are defined above. These antibiotics are useful as antibacterial and antiprotozoal agents in mammals, including man, as well as in fish and birds. The invention also includes novel compounds made by the preparation of the macrolide antibiotic.