Process for the preparation of beta hydroxy-delta lactone using novel intermediates

Process for the preparation of beta hydroxy-delta lactone using novel intermediates

The present invention relates to a process for the preparation of optically active 6-hydroxymethyl-4-tert-butyldimethylsilyloxy)-(4S,6R)-tetrahydro-2H-2-pyranone (beta Hydroxy delta Lacone) and the compound 3-oxo-5-(tert.butyldimethylsilyloxy-(1S-5S)-cyclohexylacetate having the formulathe compound...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: GHORPADE SANDEEP RAGHUNATH, KALKOTE UTTAM RAMRAO, BHIDE SUNIL RAMCHANDRA, CHAVAN SUBHASH PRATAPRAO, RAVINDRANATHAN THOTTAPPILLIL
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:The present invention relates to a process for the preparation of optically active 6-hydroxymethyl-4-tert-butyldimethylsilyloxy)-(4S,6R)-tetrahydro-2H-2-pyranone (beta Hydroxy delta Lacone) and the compound 3-oxo-5-(tert.butyldimethylsilyloxy-(1S-5S)-cyclohexylacetate having the formulathe compound 3-hydroxy-5-(tert,butyldimethylsilyloxy)-(3R,5S)-cyclohexan-1 having the formula