Hyperbactericidal surfaces

A surface is provided with antibiotic or antiseptic properties. A solid substrate is modified by covalently fixing one or more spacers having reactive extremities via a proximate reactive extremity, and one or more antibiotic, bactericidal, viricidal or fungicidal molecules covalently bonded to a di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RONDELEZ FRANCIS, BEZOU PASCAL, BOULOUSSA OTHMAN
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:A surface is provided with antibiotic or antiseptic properties. A solid substrate is modified by covalently fixing one or more spacers having reactive extremities via a proximate reactive extremity, and one or more antibiotic, bactericidal, viricidal or fungicidal molecules covalently bonded to a distal reactive extremity of the spacer or spacers. The spacer has formulawhere:A1 iswhere Z=H, OH or Cl; or SiY3 where Y3 is Cl or an alkoxy group containing 1 to 3 carbon atoms;n is in the range 2 to 18;A2 is selected from the following residues: CH=CH2, OH, halogen orwhere Z=H, OH or Cl.