Biphenyl compounds and use thereof as oestrogenic agents

Biphenyl compounds and use thereof as oestrogenic agents

A compound having the formulawherein R5 is an [A]-CH3, -[A]-C(OH)ZZ' or -[A]-C(O)Z'' grouping where -[A]- is an alkylene, alkenylene or alkynylene radical or a single bond, and Z, Z' and Z'' are a hydrogen atom or an optionally substituted alkyl, alkenyl, alkynyl or ary...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: TEUTSCH JEAN-GEORGES, LESUISSE DOMINIQUE
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:A compound having the formulawherein R5 is an [A]-CH3, -[A]-C(OH)ZZ' or -[A]-C(O)Z'' grouping where -[A]- is an alkylene, alkenylene or alkynylene radical or a single bond, and Z, Z' and Z'' are a hydrogen atom or an optionally substituted alkyl, alkenyl, alkynyl or aryl radical; and R1, R2, R3, R4, R6, R7 and R8 are as defined in the description; the use thereof as a drug, pharmaceutical compositions containing same, a preparation method therefor, and intermediates of said method, are disclosed.