Treatment of alzheimer's disease employing inhibitors of cathepsin D

This invention provides novel benzylidene rhodanines which are useful as agents in treating or preventing conditions associated with beta-amyloid peptide. This invention further provides methods of treating or preventing Alzheimer's Disease which comprises administering to a mammal in need ther...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	REEL JON K, SIGMUND SANDRA K, PANETTA JILL A, SHADLE JOHN K, SIMON RICHARD L, PHILLIPS MICHAEL L, WHITESITT CELIA A
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention provides novel benzylidene rhodanines which are useful as agents in treating or preventing conditions associated with beta-amyloid peptide. This invention further provides methods of treating or preventing Alzheimer's Disease which comprises administering to a mammal in need thereof an effective amount of one or more of the benzylidene rhodanines of the present invention.