N-substituted azaheterocyclic carboxylic acids and esters thereof

The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment...

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Hauptverfasser: ANDERSEN KNUD ERIK, MADSEN PETER, HOHLWEG ROLF, ZDENéK POLIVKA, JOERGENSEN TINE KROGH, ANDERSEN HENRIK SUNE, OLSEN UFFE BANG, DOERWALD FLORENZIO ZARAGOSSA, KAREL SINDELáR, TREPPENDAHL SVEND, ALEXANDRA SILHáNKOVá
Format: Patent
Sprache:eng
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Zusammenfassung:The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.