Tricyclic pyrazolo-pyridazinone analogues as GAGA-A receptor ligands

Tricyclic pyrazolo-pyridazinone analogues as GAGA-A receptor ligands

Pyrazolo[4,3-c]pyridazin-3-one analogues, represented byare selective ligands for GABAA receptors, in particular having high affinity for the alpha2 and/or alpha3 subunit thereof, are useful in the treatment of anxiety and convulsions.

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Bibliographische Detailangaben
Hauptverfasser: BLURTON PETER, FLETCHER STEPHEN ROBERT
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:Pyrazolo[4,3-c]pyridazin-3-one analogues, represented byare selective ligands for GABAA receptors, in particular having high affinity for the alpha2 and/or alpha3 subunit thereof, are useful in the treatment of anxiety and convulsions.