Process for preparing pharmaceutically active compounds and intermediates thereof

A process is disclosed for the preparation of (1) by reduction of (2) directly using catalytic transfer hydrogenation to suppress formation of (4) or by conventional reduction via (4). Compound (1) is a key intermediate for inter alia paroxetine.

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Bibliographische Detailangaben
Hauptverfasser: LATHBURY, DAVID CHARLES, ENNIS, DAVID S
Format: Patent
Sprache:eng
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Zusammenfassung:A process is disclosed for the preparation of (1) by reduction of (2) directly using catalytic transfer hydrogenation to suppress formation of (4) or by conventional reduction via (4). Compound (1) is a key intermediate for inter alia paroxetine.