Sox-9 gene and protein and use in the regeneration of bone or cartilage

PCT No. PCT/AU95/00799 Sec. 371 Date May 29, 1997 Sec. 102(e) Date May 29, 1997 PCT Filed Nov. 29, 1995 PCT Pub. No. WO96/17057 PCT Pub. Date Jun. 6, 1996An isolated DNA molecule encoding a Sox-9 gene which codes for the Sox-9 polypeptide. The human Sox-9 gene has been mapped to chromosome 17 in the...

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Hauptverfasser:	KOOPMAN, PETER ANTHONY, GOODFELLOW, PETER NEVILLE
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Zusammenfassung:	PCT No. PCT/AU95/00799 Sec. 371 Date May 29, 1997 Sec. 102(e) Date May 29, 1997 PCT Filed Nov. 29, 1995 PCT Pub. No. WO96/17057 PCT Pub. Date Jun. 6, 1996An isolated DNA molecule encoding a Sox-9 gene which codes for the Sox-9 polypeptide. The human Sox-9 gene has been mapped to chromosome 17 in the same region as CMPD-1, the locus for Campomelic Dysplasia (CD). Sox-9 appears to have a role in mammalian skeletal development, and is used in the treatment of diseases involving bond or cartilage deficiency.