Iontophoresis system and its control process of current

PCT No. PCT/JP96/02286 Sec. 371 Date May 5, 1998 Sec. 102(e) Date May 5, 1998 PCT Filed Aug. 12, 1996 PCT Pub. No. WO97/07853 PCT Pub. Date Mar. 6, 1997An iontophoresis system and its control process for current are proposed, which system can decrease variation in drug delivery quantity due to the i...

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Hauptverfasser: MORI, KENJI, NAKAMURA, KATSUHIRO, HIGO, NARUHITO, KUZUMAKI, NORIYUKI
Format: Patent
Sprache:eng
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Zusammenfassung:PCT No. PCT/JP96/02286 Sec. 371 Date May 5, 1998 Sec. 102(e) Date May 5, 1998 PCT Filed Aug. 12, 1996 PCT Pub. No. WO97/07853 PCT Pub. Date Mar. 6, 1997An iontophoresis system and its control process for current are proposed, which system can decrease variation in drug delivery quantity due to the individual difference of impedance of skin or mucosal membrane, and avoid any decrease of the delivery quantity of drug in a donor device, thereby to obtain excellent medicinal effect, safety, reliability, and productivity, comprising said donor device, a reference device, a current detection unit for measuring as an effective current value the difference between the value of an applied current passing between the donor and reference devices during application of pulse voltage/current and the value of a discharged current whose electric charge which the living body has been equipped with is released by a short-circuit formed between said donor and reference devices when the application of pulse voltage/current is suspended, and a feedback control unit of making the amplitude of the pulse voltage/current variable to control the effective current value. The control process for current of the iontophoresis system of the present invention comprises an effective current measurement step of measuring said effective current value and a feedback control step of controlling said effective current value.